ABSTRACT

Extraosephageal reflux has been identified as a common pediatric disorder with airway symptoms. Extraosephageal reflux may cause manifestations as asthma, recurrent pneumonia, chronic cough, recurrent croup, otitis media, laryngomalacia and apnea. Multichannel intraluminal impedance and pH monitoring study has recently been shown that significant proportion of non-acid reflux may precede cough episodes in young children with chronic cough. Diagnostic testing with multichannel intraluminal impedance and pH monitoring should be reserved for those unresponsive to acid suppressive therapy. Impedance/pH monitoring performed under proton pump inhibitor therapy may be useful to help elimination of extraesophageal reflux as the cause of persistent respiratory symptoms.