Health Risks Posed by Use of Di-2-Ethylhexyl Phthalate (DEHP) in Medical Devices


  • Sevcan Atay

Received Date: 13.07.2012 Accepted Date: 28.11.2012 J Pediatr Res 2014;1(3):113-117

Polyvinyl chloride plastics, made flexible through the addition of di-2-ethylhexyl phthalate, are used in the production of a wide array of medical devices. Animal studies demonstrated that exposure to di-2-ethylhexyl phthalate (DHEP) can damage the liver, kidneys, lungs, and reproductive system, particularly the developing testes of prenatal and neonatal males. Especially early in life di-2-ethylhexyl phthalate exposure may adversely affect male reproductive tract development. Thus, the United States Food and Drug Administration has issued a Public Health Notification on Polyvinyl chloride plastics devices containing di-2-ethylhexyl phthalate, urging health care providers to use di-2-ethylhexyl phthalate -free devices for certain vulnerable patients.

Keywords: Di-ethylhexyl phthalate, polyvinyl chloride, medical device

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